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All five trials met the primary objective of excluding an increased risk of cardiovascular disease in patients treated with DPP-4 inhibitors, however, none were associated with any cardiovascular benefit ( GLP-1 Receptor Agonists The cardiovascular safety of GLP-1RA have been assessed in seven clinical trials enrolling 60,090 patients (7780)

PMID: 178 Valencia-OrtegaJZrateASaucedoRHernndez-ValenciaMCruzJGPuelloE

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Current research suggests that a varied diet including sulfur-rich vegetables, fresh produce, and quality protein sources may help provide dietary glutathione and supporting nutrients