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GLP1 prevented increases in the atrial effective refractory period, P-wave duration, atrial conduction time, atrial conduction velocities and action potential duration, which were observed in dB/dB mice

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doi: 10.1080/21688370.2023.2292461

Expanding that framework, or developing alternatives that achieve similar outcomes for the commercially insured population, will require policy innovation that moves faster than the current rate of change

hence, GLP-1 agonists could be started in primary or secondary care

In 2023, after a 40 percent rebate, the SHP spent $102.3 million on GLP-1s for weight loss, approximately 10 percent of the programs pharmacy expenditures