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Beyond absorption timing, reduced caloric intake from decreased appetite means fewer opportunities to consume nutrient-dense foods

People who have severe gastrointestinal conditions like inflammatory bowel disease (IBD) or gastroparesis should not go on GLP-1s, and neither should people with a personal or family history of multiple endocrine neoplasia 2A, multiple endocrine neoplasia 2B, medullary thyroid cancer, or pancreatitis

By consolidating data and demonstrating their effectiveness, CDFIs can make a strong case for increased support, ensuring that they can continue to play a vital role in fostering economic growth and opportunity in underserved communities

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In research models the two mechanisms are reported to act synergistically