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Preclinical safety evaluations revealed no toxicity in acute studies with SD rats and beagles following intravenous/intramuscular administration [10]

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Evans JL, Goldfine ID, Maddux BA, Grodsky GM (2003) Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction

"The structure and function of the glucagon-like peptide-1 receptor and its ligands"