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These divergent effects on ARE-bindings were reflected in the expression of AR-dependent genes that were impacted by SUMOylation: genes activated by AR negatively regulate cell proliferation, and those repressed by AR are involved in pattern formation by WNT, TGF-B, and FGF signaling [74]

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The blue light emitted by phones, tablets, and other screens suppresses melatonin, delays sleep, and reduces the amount of deep sleep your brain gets