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Clinical Data Clinical data for the analysis were taken from the SUSTAIN trial program, specifically the SUSTAIN 3 and SUSTAIN 7 trials, comparing once-weekly semaglutide 1.0 mg with exenatide ER and once-weekly semaglutide 0.5 mg and 1.0 mg with dulaglutide 0.75 mg and 1.5 mg, respectively (Table 1) [15, 16]

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Molecular pharmacology 72, 463476, doi: 10.1124/mol.107.037630 (2007)

Tirzepatide is studied as a dual agonistmeaning it activates both the GIP receptor (one incretin pathway) and the GLP-1 receptor (another incretin pathway)

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