& Miller, L
How It Works: Specific amino acidsparticularly leucine, glutamine, and argininebind to G-protein coupled receptors on L-cells, initiating a cascade of cellular signals that result in proglucagon processing and GLP-1 release
In vitro studies demonstrated that treatment with liraglutide or exendin-4 significantly attenuated oxidative stress and cellular apoptosis in SH-SY5Y cells exposed to methylglyoxal or high glucose, which mimicked the pathophysiological conditions of diabetic neuropathy [79, 80]
Michael Buontempo, a resident physician at Dartmouth-Hitchcock Medical Center, explains: Most hair shedding on GLP-1s looks like androgenetic alopecia unmasked by an episode of telogen effluvium driven by the magnitude of weight loss, rather than a direct drug toxicity. This means some people discover they have genetic hair loss when the telogen effluvium pulls away enough hair to reveal the underlying pattern
When the medication handles the physical side, these emotional patterns do not disappear
E.TsaousidouE.HalloranJ.FollettP.HahnO.PereiraM
