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Weight distribution and biomechanics : As body weight decreases, gait patterns and joint loading change

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The factors which are to be considered for dose estimation by transdermal route are discussed in the literature and are in general as enumerated in table 1 Table 1: Factors for consideration for Transdermal Dose Calculation Thus, dose calculation requires thorough consideration of all above factors

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The use of these drugs for weight loss has particularly surged in recent years, as they have been marketed as effective tools for managing obesity