To measure the concordance between manual classification and model prediction, we manually scored 19% of all cells from each cluster identified by the model (Methods), which gave us an accuracy value ranging from 75% for erythrocytes to 96% for polynucleated giant cells (Extended Data Fig
Appetite suppression at 2.5 mg is modest, so the gastric emptying and dietary mechanisms are less pronounced
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Protein thiol homeostasis: Glutathione maintains proteins in their reduced (functional) state through S-glutathionylation, a reversible post-translational modification that regulates protein activity under oxidative stress [2]