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, aminopeptidases) that can degrade susceptible peptides and proteins, while the olfactory mucosa and olfactory bulb expresses xenobiotic-metabolising enzymes (including multiple CYP isoforms and phase II enzymes) (Minn et al., 2002)

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CSA-13 dose-dependently regulates the permeability of human umbilical vein endothelial cells (HUVECs) monolayers as well as affects the secretion of cytokines, which may indicate its ability to modulate immune responses