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et al (2015) Oncol Lett.

A newly published peer-reviewed scientific paper from China adds to the growing body of evidence around the benefits that dorzagliatin (GKA) in combination with the popular semaglutide (GLP-1RA) delivers superior glycemic control, weight reduction, and islet cell function improvement when compared with semaglutide monotherapy in obese patients with Type 2 diabetes mellitus (T2DM), with a comparable safety profile

The answer is more nuanced than a simple yes or no

PMCID: PMC10561660

doi: 10.1111/j.1365-2265.2010.03904.x 42 BouzasEAKaradimasPMastorakosGKoutrasDA

Dosage Precautions Treatment with this drug should be administered with caution if the animal has chronic renal failure