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Ferroptosis: Role of lipid peroxidation, iron and ferritinophagy

They used recombinant adenoviruses to express CREBH-C in mice, and it was detected in various metabolic organs and tissues, including the liver, blood, white adipose tissue, skeletal muscle, heart, and kidneys

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It is studied in preclinical trials that MC4R is predominantly expressed in hypothalamic nuclei and has extensive published documentation of its role in energy homeostasis and appetite regulation pathways