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Topamax inhibits carbonic anhydrase, which can lead to metabolic acidosis and increased risk of kidney stones, whilst Ozempic's gastrointestinal effects may lead to dehydration if vomiting or diarrhoea is severe

The basal insulin dose was decreased by 20% at randomization and liraglutide injection was titrated weekly by 0.6 mg for 2 to 3 weeks based on tolerability and an average fasting plasma glucose goal of 110 mg/dL

volume agent: dicalcium phosphate