Whilst glucagon typically raises blood glucose, early Phase 2 trial data suggest that, when combined with GLP-1 receptor activation, its net effect may include increased calorie burning and a potential reduction in liver fat, without causing clinically significant rises in blood sugar
Gelbart M, Friedman R, Burlui V, Rohrer M, Atkinson B
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Hengrui Leads Oral GLP-1, Shanghai New Cell Therapy Policy: China biotech Weekly Roundup Jiangsu Hengrui has won NMPA approval to begin clinical trials of an oral smallmolecule GLP1 receptor agonist, HRS7535, targeting hypertension with overweight/obesitymarking a major step in Chinas fastgrowing oral GLP1 race and positioning Hengrui as a leading local competitor to global players
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