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Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles in vitro

The result: Increased lipolysis : Fat cells release stored fatty acids for use as fuel Inhibited lipogenesis : Dietary fats are less readily converted to stored body fat No significant IGF-1 stimulation : Means no growth of existing tumors or cancer risk amplification that concerns some clinicians with full GH No significant glucose disruption : Unlike full HGH, which causes insulin resistance at therapeutic doses, AOD-9604 shows minimal glucose impact in studies This makes it uniquely well-suited for fat loss use cases where full HGH would be too blunt an instrument

fibronectin (Abcam, ab45688, clone F14, lot 1016266-35, WB, 1:1,000, Hu)

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[9] Diastolic reductions were proportionally smaller, around 8 mmHg, consistent with a vasodilatory mechanism acting on resistance arteries rather than a cardiac-output effect