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Croal BL, Glen AC, Kelly CJ, Logan RW: Transient 5-oxoprolinuria (pyroglutamic aciduria) with systemic acidosis in an adult receiving antibiotic therapy

Techniques such as XRD and dynamic light scattering provide information on crystallinity and hydrodynamic size, but are often unreliable for amorphous or highly polydisperse CQD formulations, further highlighting the need for harmonised, cross-validated analytical protocols [167]

While ROS can function as second messengers regulating cellular reproduction, growth, differentiation, and signaling when maintained at optimal concentrations and dynamic equilibrium, exceeding critical ROS thresholds induces oxidative stress, leading to DNA damage, protein denaturation, and lipid peroxidationkey factors in CHD development

10.1016/s0092-8674(00)81369-0 67 MangoniA.GrassiM

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In addition, natural activators of NRF2, such as indole, diterpenes, coumarin and lactone, alleviate renal cell death induced by lipid peroxidation [213]