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(2) molecular dynamics simulated annealing restraining FOXO4 FH (without flexible regions) harmonically to its template structure (using a non-crystallographic force constant of 10,000 kcal mol 1 2 ), with additional dihedral angle restraints from 1 H, 15 N, and 13 C chemical shifts using TALOS-N 56 , hydrogen bond restraints (region p53 residues 48-55

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That said, reassurance is not the same as dismissal

Herold et al., 2019

We are thrilled to be part of this cutting-edge research made possible by the observational facilities provided by ESO. After two decades of hunting for exoplanets, we are finally beginning to see long-period gas giant planets similar to those in our own solar system thanks to the long-term stability of planet hunting instruments like HARPS, said Megan Bedell from the University of Chicago