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1 2 3 4 5 6 7 8 9 10 11 Institute of Medicine (1998)

P 10 years younger compared with that of the non-melanoma group

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SURMOUNT-4 patients lost 20.9% by week 36

Endothelial dysfunction impairs hepatic circulation, increasing portal hypertension and leading to complications such as ascites, variceal bleeding, and hepatic insufficiency (122)

[Yakugaku Zasshi