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A substance must receive a marketing authorisation demonstrating safety, efficacy, and quality before it can be legally sold or supplied as a medicine

Membranes were finally incubated with HRP conjugated secondary antibodies and developed with a chemiluminescent reagent (Biorad, California, USA)

doi: 10.1186/s41043-023-00374-6 185 MatsushitaMFujitaKHayashiTKayamaHMotookaDHaseHet al

doi: 10.1210/clinem/dgac577 7

Left unchecked, free radicals damage cells and contribute to the development of serious health problems such as Hashimotos hypothyroidism

Of these redesigns, 33 (40%) were at least as active and as highly expressed as WT BoNT/E (Extended Data Fig