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in vitro testing, large agglomerates of 17 nm TiO 2 caused stronger toxicity responses including glutathione depletion, IL-8 and IL-1 increase, and DNA damage in monocytic cell lines, compared to small agglomerates

For validation, we examine resistance measurements and marker molecule expression

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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

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