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Although weight was likely a significant contributor to the disease pathogenesis, the time required for weight loss through diet or even bariatric surgery would not have been rapid enough to address the severity of the papilledema and risk to vision

The ratio of GSH (reduced) and its disulfide, GSSG (oxidized), contributes to the redox potential of the cell and thereby contributes to redox homeostasis (Fig

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modifying lifestyles, such as physical exercise and diet, can address many causative factors contributing to MetS

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