19, 20 The latter observation led to a recently completed phase I trial of BSO+L-PAM given with stem cell support in the New Approaches to Neuroblastoma Therapy (NANT) consortium that has safely dose-escalated L-PAM given with BSO to myeloablative L-PAM doses, with the stem cell infusions overcoming the expected hematopoietic toxicity (www.NANT.org
Inconsistent timing can cause valleys in drug concentration, potentially weakening the medication's effect and making hunger management harder
On the contrary, the FDA has questioned the safety of the hCG diet as well as OTC hCG products
When delivered transdermally (on the skin), it is difficult for the skin to absorb fully
La terapia farmacologica funziona meglio se integrata in un approccio multidisciplinare (nutrizione, movimento, supporto psicologico)
de Jager J, Kooy A, Lehert P, Wulffele MG, van der Kolk J, Bets D, Verburg J, Donker AJ, Stehouwer CD