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41 In our study, ACE effectively induced ferroptosis in tumor cells by increasing the intracellular Fe 2+ concentration

4f, the naphthyl core of 27 is found deep in the leucine pocket of the TIN2 TBM site, with the negatively charged sulfonic acid group forming strong electrostatic interactions with the positively charged side chains of R102 and R131 on either side of the pocket

In other words, it should only be used as a vehicle for other drugs, not as fluid replacement

Vascular Signaling: Angiogenesis, endothelial response, and nitric-oxide pathway activity

The VEGF family of angiogenic growth factors is involved in neuroprotection, neurogenesis, and angiogenesis

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