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Less pain or anxiety: For those who experience discomfort with injections, a patch may provide a needle-free alternative

Prescribed GLP-1 medications use the same FDA-approved sites as compounded semaglutide: abdomen, front thigh, and upper arm

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Additionally, tirzepatide acts on areas of the brain involved in appetite regulation, leading to reduced hunger and increased feelings of fullness

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Glucose-sensing leads to membrane depolarization and calcium entry through voltage-gated channels, leading to exocytosis of GLP-1-containing vesicles (27)