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Overall, 14 cases provided structural descriptions, and cystic or necrotic changes were mostly observed in larger sized tumors ( 5 cm, 7/9, 77.7%) but less frequently noted in the smaller sized tumors ( 2 mitosis/10 HPF should receive adjuvant therapy [34]

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However, because some estimates were imprecise, particularly for rarer outcomes of major congenital malformation and small birth size, the authors said further research would be valuable to better understand the safety of GLP-1s in pregnancy