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Certain medicines including mirtazapine, some antipsychotics such as olanzapine, corticosteroids, and some diabetes treatments are well recognised to cause weight gain or impair weight loss

doi: 10.1089/rej.2018.2077

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These compelling results underscore TERN-601s potential to be a class-leading GLP-1R agonist based on its composite profile of initial indications of efficacy, tolerability and manufacturing scalability, said Burroughs

Nutrients 14, 1388

In this investigation, we initially identified oridonin as a direct covalent inhibitor of GSH, setting it apart from other drugs that disrupt ROS by targeting proteins both upstream and downstream of GSH