For musculoskeletal injury, including tendon tears, ligament sprains, and muscle strains, the preclinical evidence is most extensive and the extrapolated human dosing most confident
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Significant main effects of treatment group (prior to BenjaminiHochberg correction since none were significant after correction, although the necessity of correction for multiple comparisons in exploratory analyses remains unresolved 49 ) were observed for the unclassified group and ten classified genera, namely, Acetatifactor , Akkermansia , Erysipelatoclostridium , [ Eubacterium ] coprostanoligenes group , Family XIII UCG-001 , Lactobacillus , Parasutterella , Ruminiclostridium 6 , Ruminococcaceae UCG-004 , and Ruminococcaceae UCG-009
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It has been observed to promote angiogenesis and stimulate granulation tissue formation, and accelerate extracellular matrix remodeling, particularly in models of skin, muscle, and gastrointestinal injury (Seiwerth et al
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