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The success of these interventions relies on the effective management of side effects and nutritional challenges

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For models with within-subjects factors (i.e., the body mass models), the Greenhouse-Geisser corrected was used if sphericity violations occurred

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Conclusions Changes in intra-portal insulin levels play an intricate yet permissive role in the regulation of the GH/IGF-I axis by either stimulating or suppressing hepatic GH sensitivity and hepatic IGF-I generation, probably via an insulin-mediated regulation of the hepatic GHR expression

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