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Truly elevated cortisol is associated with Cushings syndrome, a rare disorder caused by steroid medications or tumors of the pituitary or adrenal glands 2

The study documented that beneficial effects persisted for several days after treatment cessation, suggesting modification of underlying sleep regulatory mechanisms rather than simple sedation

doi: 10.1097/med.0000000000000497 73 QinYZhangDZhangHHouLWangZYangLet al

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Effective for racing thoughts, Sleep Deprivation Reduces Testosterone and Estrogen Sleep deprivation directly reduces both testosterone and estrogen production

This small randomized, double-blind, placebo-controlled trial showed significant improvements in fatigue, as measured by the Chalder Fatigue Questionnaire eleven-item scale and in the six-minute walk test endpoint (153)