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Arginine at position 244 does not interfere with Glu235 and the substrate-deprotonation-process, as indicated by significantly lower K m values for Leu244Arg compared to Asn240Lys (Table 2)

Roy A, Dawson V, Dawson T

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All studies seem to have reported all data which gives a low risk of incomplete outcome data as "attrition bias"

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Summary: Saxenda does not directly lower cholesterol but may lead to modest improvements in lipid profiles indirectly through the weight loss it facilitates