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However, bioavailability through topical application remains limited compared to injectable delivery

2023 Jun;13(6):27012714

Because high-quality human data are limited, there is no universally accepted clearance time, so we emphasize individualized dosing, careful monitoring, and regular re-evaluation rather than assuming it is quickly or completely out of the system after a set number of days

In general, serious side effects from B12 injections are rare but in some cases, people may experience a few mild ones including pain, redness, or bruising at the site of injection

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The Journal of Clinical Investigation