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RAND researchers surveyed 8,793 adults of the RAND American Life Panel to ask about use of GLP-1 drugs and their experiences with side effects

That said, mild effects can occur in some people, especially when starting any new supplement: Temporary bloating or fullness (more common with collagen) Mild digestive discomfort if taken without enough water These are usually short-lived and can be reduced by: Taking supplements with adequate water Starting with recommended doses Choosing high-quality, well-absorbed formulations Using clinically formulated products from trusted brands helps minimize unnecessary reactions

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PloS one.2016;11(6):e0156773

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Nature 517 , 360364 (2015)