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Severity of BED was determined based on having at least 3 binge days per week for 2 weeks prior to the baseline visit and on having a Clinical Global Impression Severity (CGI-S) score of 4 at the baseline visit

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Unless you're actively adding salt to your food, you're likely consuming far less sodium than your body needs.People on low-carbohydrate diets excrete more sodium in urine, further increasing sodium requirements.So if you're eating mostly whole foods on a GLP-1 RA, you'll likely need to intentionally add sodium to meet your body's needs.ExerciseIf youve increased your physical activity, you will lose more sodium, chloride, and potassium through sweat.Compounding the issue is that more intense or longer exercise sessions can also cause you to lose even more of these electrolytes, especially if performed at higher temperatures

Of these, the overproduction of apoptotic vesicles and increased calcification of cartilage tissue can induce cellular pyroptosis, thereby exacerbating osteoarthritis (163)