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The primary outcome, fatigue, measured using the BFI, improved in both arms compared with baseline (L-carnitine: 0.96, 95% CI, 1.32 to 0.60

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However, the substantially better efficacy (concerning HbA 1c and BW reductions) compared to semaglutide at the standard dose used in most type 2 T2D trials was the most remarkable finding (85, 86)