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Clinical trials, including research in diabetic hyperlipidemic patients on dialysis, have reported meaningful reductions in total cholesterol, very-low-density lipoprotein cholesterol (VLDL-C), and triglycerides at doses around 900 mg per day

In several key meta-analyses cited in this review (97, 125, 126), I 2 statistics exceeded 50%, indicating substantial heterogeneity that was not fully explained by pre-specified subgroup analyses

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All authors have made a significant contribution to this study and have approved the final manuscript.

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