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Standard-dose semaglutide is generally designed for more traditional GLP-1 weight loss treatment with gradual dose escalation

Clinical outcomes (change in HbA 1c , weight, BMI, eGFR and cholesterol, compared with baseline) were recorded and analysed from 3 months to 3 years post index date

GLP-1 medications carry risks including gastrointestinal symptoms, pancreatitis, and gallbladder disease, requiring specialist supervision

A larger evidence synthesis also supports Tirzepatide s strong efficacy while noting expected gastrointestinal side effects

(2002) in the Journal of Clinical Endocrinology and Metabolism

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