A review of 38 RCTs comprising 7,551 patients on ICI therapy evaluated the incidence of endocrine irAEs and found a higher incidence of hypo and hyperthyroidism, especially in patients receiving combined ICI therapy (OR: 3.81
Caceres JA, Goldstein JN
Its vital to have a dedicated partner who understands these technicalities and can adjust your protocol accordingly
The aspartic acid residue is highly susceptible to dehydration, forming a cyclic imide that can then hydrolyze into either the original form or an inactive iso-aspartate analog
Consultation: During your initial consultation, our medical professionals will discuss your health history, assess your current Vitamin B12 levels, and understand any specific concerns you may have
When ER zinc balance is disrupted, ER stress pathways become activated, triggering the unfolded protein response (UPR) 121,122