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Since GLP-1-induced insulin secretion requires glucose metabolism, we aimed to address the hypothesis that GLP-1 receptor (GLP-1R) signalling can modulate glucose uptake and utilization in -cells

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RAGE although functionally a PRR, exhibits distinct structural and functional characteristics that preclude its classification into the traditional five families and instead places it within the immunoglobulin superfamily

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Yet, measures of specific neuropathic impairments (secondary outcomes) improved with lipoic acid supplementation (78)