demonstrated that in dendritic cells (DCs), LPS-induced glycolysis is repurposed to replenish citrate, an intermediate metabolite in the TCA cycle that is depleted for the de novo synthesis of fatty acids ( 2 ( de novo lipogenesis is important for phagocytosis as it requires ongoing lipid synthesis in the ER for membrane expansion, such that Ms can surround and capture targeted pathogens for internalization ( de novo lipogenesis, an anabolic process that is NADPH-dependent, in regulating the inflammatory response of myeloid cells
Results at Week 30 in a Trial of OZEMPIC as Monotherapy in Adult Patients with Type 2 Diabetes Mellitus Inadequately Controlled with Diet and Exercise a The intent-to-treat population includes all randomized and exposed patients
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