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Electroacupuncture at the Tianshu (ST25) point can alleviate PD-associated constipation by enhancing the autophagic state within the enteric nervous system, protecting enteric neuronal function, and regulating intestinal motility

Finally, melatonin could help alleviate neurological complications such as brain fog, ME/CFS, anxiety, and sleep disorders

Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity

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Mitoses near the base of the lesion and atypical mitoses are further indicators of malignancy [107]