2 GLP-1RAs taken once weekly may take four to five weeks to achieve steady state, while clinical effectiveness may be longer depending on many factors such as age, sex, body weight, and liver and kidney function
Most patients experience mild nausea, reduced appetite, and occasional loose stools during the first 24 weeks as their body adjusts
Reported observations include: Localized injection-site reactions such as redness, itching, or mild swelling
Other plans require prior authorization, documented failed attempts with older medications, or a BMI above 30 with obesity-related complications before approving coverage
What happens if I'm not a candidate for the medication
3A), suggesting that the E3 ligase activity of NEDD4 is required for this regulatory process