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3D variability analysis: resolving continuous flexibility and discrete heterogeneity from single particle cryo-EM

Major depressive disorder: hypothesis, mechanism, prevention and treatment

A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice

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Longevity-focused wellness is about maintenance, not extremes Modern wellness increasingly focuses on: Supporting how the body functions over time, rather than only short-term cosmetic outcomes

In addition to generating damaging oxidative molecules, excess cholesterol will lead to reduction of membrane fluidity and disrupt signalling from lipid rafts, which are cholesterol and sphingolipid rich structures in the plasma membrane that regulate the assembly and functioning of numerous cell signalling pathways and contribute to their proper function [9]