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A positive development is that the estimated prevalence of AMD in Americans 40 and older has decreased from 9.4% in the years 1988-1994 to 6.5% in the years 2005-2008 (Klein 2011)

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It can be specifically internalized by M1 cells, release ART and DEX, scavenge ROS, inhibit the HIF-1/NF-B pathway, and mediate repolarization of macrophages

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