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At high pharmacological doses (used historically to lower cholesterol), niacin also affects lipid metabolism, as described in a clinical study

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Related article: Histamine intolerance genes Mast cell triggers and mediators: Researchers have found that there are a variety of substances within the body that will trigger mast cells to release mediators without complete degranulation

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Therefore, regulating tumour progression hinges on maintaining ROS below the critical threshold that supports oncogene dependence [23], on the basis of which targeted regulation of SOD activity is regarded as a potential strategy in cancer treatment [24]

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