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The MHRA has warned that this may increase the risk of residual stomach contents during general anaesthesia or deep sedation, even after standard fasting

Because statin efficacy depends on sustained hepatic HMG-CoA reductase inhibition (an AUC-driven effect, not a Cmax-driven effect), the interaction is not clinically meaningful

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Over the extra week without an injection, levels fall well below the normal trough, following the same exponential math as the accumulation table above

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