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221 This is the case of MKN28 cancer cell line, where no mRNA nor protein expression was found due to high methylation of NAPRT promoter region

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Glutathione peroxidase 1 (GPX1) is one of the most abundant members of the GPXs family that protects cell from oxidative damage and maintains the balance of intracellular redox systems ( Ebselen [2-phenyl-1,2-benzoisoselenazol-3(2H)-one] is a synthetic organoselenium radical scavenger compound that has GPX-like activity, and it can directly increase GPX1 activity to mimic the effect of GPX1 overproduction

Askari G, Nasiri M, Mozaffari-Khosravi H, Rezaie M, Bagheri-Bidakhavidi M, Sadeghi O

[DOI] [PubMed] [Google Scholar] 48.Sucic M, Luetic K, Jandric I, Drmic D, Sever AZ, Vuletic LB, Halle ZB, Strinic D, Kokot A, Seiwerth RS, Zoricic I, Blagaic AB, Seiwerth S, Sikiric P