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Eli Lilly sponsored SURMOUNT-5, (NCT05822830), a Phase IIIb, open label, multi-centre, randomised clinical trial to compare the efficacy and safety of tirzepatide (Zepbound) versus semaglutide (Wegovy) in overweight or obese adults and at least one additional named weight-related comorbidity that was not T2D 24
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Additionally, the high cost of these medications remains a major barrier, requiring policy changes to ensure broader insurance coverage and affordability
Virta now commits to stopping these increases completely, guaranteeing 0% utilization growth for employers offering this drug class for obesity
While GLP-1s and similar peptides famously suppress appetite, reduce blood sugar, and cause weight loss, a growing body of research suggests they might also do much more: curb inflammation all over your body, increase mitochondria in skeletal muscle to give you more energy and help you build strength, and reduce the risk of conditions ranging from Alzheimers to heart disease to alcohol use disorder
We can also infer from this that GLP-1 drugs could remain an option for the wealthy cohort of the population
