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Without enough vitamin B12, red blood cells may have trouble getting out of the bone marrow because they will not divide normally and are too large to move into the bloodstream

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It is important to establish specific systemic biomarkers which can easily be monitored in the clinic, serve as a novel diagnostic tool, or verify treatment efficacy for ALS [40]

SNIP1 has also been implicated in transcription regulation and oncogenesis 50,51,52,53,54,55 , highlighting its clinical relevance