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The combined effect of these modifications increase the drugs half-life from minutes to approximately 168 hours, enabling its once-weekly injection schedule an enormous improvement compared to the twice daily injection required for exenatide (Byetta) which was the first GLP-1 drug that was launched

Many patients find room-temperature storage more convenient for weekly injections, as refrigerated needles can feel uncomfortable during injection

While they offer promising results in controlling blood sugar and aiding weight loss, misuse or overuse could pose significant health risks.