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They are delivered by the peptide administered at the right dose, through the right route, from a pharmaceutical-grade source, to a patient whose indication has been properly assessed, with activity guidelines in place that prevent the danger zone re-injury that the peptides anti-inflammatory effect makes possible

In high doses, the most serious adverse effect is a dose-dependent, potentially fatal hepatic necrosis

Importantly, the weight-reducing efficacy appears comparable to that observed in common, polygenic obesity, as preliminarily evidenced by subgroup analyses from large trials such as SURMOUNT-1

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